Janet "Prissy" Gregory, a single mother with a haunted past, is a paralegal struggling to overcome doubts about the culpability of Calvin Willis, an African-American husband and father wrongfully accused of assaulting a neighborhood girl. Eventually convinced of Calvin's innocence, Janet decides, at great personal cost, to take on his case and fight for him when many of those closest to him turned their backs. Despite seemingly insurmountable odds, she wages a 22-year battle against the justice system, enlisting the help of The Innocence Project, an organization that works to exonerate wrongfully convicted people through DNA testing.