Twenty-something April, a smart and quick-witted aspiring journalist, is trying to work her way up the ladder at a Boston newspaper by impressing her hard-nosed editor. When not pursuing the latest scoop, April tries to balance career with her family, which includes her widowed mom Sara, rebellious little sister Brenna and her grandmother. Just as things start to look up at work, at home and on the romance front, however, April learns that she has cancer.